Convalescent Plasma Therapy is also known as plasmapheresis, which is a sensation among news, media, internet, social media, and people these days. Scientists have discovered that this therapy can help in treatment coronavirus. So let’s know what this plasma therapy is and how it can be used to prevent the Coronavirus.
What is the Meaning Convalescent Plasma Therapy?
Convalescent Plasma Therapy, also known as plasmapheresis, is the removal, treatment, and return or exchange of the patient’s blood plasma. Plasma Therapy is a therapy, which takes antibodies from the blood of a person who has recovered from a virus and injects those antibodies into a person sick with that virus, has long been used as a way to help kickstart a person’s immune system.
In this therapy, small amounts of blood are slowly removed through an embedded needle or central line catheter and circulated through a machine that portion blood into a plasma substitute added to your blood cells (red cells, white cells, and platelets).
They are returned by intravenous or central venous catheter access. The plasma is discarded in a waste bag. One procedure typically removes 65 to 70 per cent of the disease-causing proteins (antibodies) in the plasma.
How does it work to fight from COVID-19?
Trials of Convalescent Plasma Therapy:
ICMR approved Convalescent Plasma Therapy for COVID-19 patients in India:
The Indian Council of Medical Research (ICMR) has concluded the research protocols for plasma therapy and has approved the use of treatment for COVID-19 patients in India. ICMR needs the approval of the Drugs Controller General of India (DCGI) before conducting the clinical trials. The DCGI permission is required for collecting the blood donation for this kind of treatment.
Trials of plasma therapy in the US:
Convalescent plasma therapy gained momentum in the United States on March 28, 2020, when the two hospitals namely Houston Methodist Hospital and Mount Sinai Medical Center, have partnered with the FDA on clinical trials on convalescent plasma and is treating three patients with the therapy. Johns Hopkins Bloomberg School of Medicine in Baltimore, Maryland, is also conducting convalescent plasma trials. However, the results are still waiting.
Trials of Convalescent plasma therapy conducted in China:
While per the tests conducted on a few patients of Coronavirus in China, the therapy came out as a hopeful opportunity for severe cases. These tests were conducted on ten patients who were given a single dose of blood plasma of recovered patients. The results showed that the Coronavirus disappeared from patients’ blood in 7 days; lung injuries improved within seven days and clinical symptoms increased significantly within three days.
Kerala to be the first state to initiate Convalescent Plasma Therapy:
PGIMER Chandigarh to soon launch trials for Plasma Therapy:
Dr Jagat Ram, Director of the Post Graduate Institute of Medical Education and Research (PGIMER) Chandigarh, recently announced that the institute would soon begin with the trials of Convalescent plasma therapy in collaboration with another COVID-19 centre.
How many patients can be treated with one donor’s plasma?
A report has come out that a person who has been cured of Coronavirus can produce two doses of Plasma therapy with his blood for transfusions. Scientists say that a person only needs one transfusion to get enough antibodies to recover entirely from the Coronavirus.